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LA DREPANOCYTOSE

6ème Math-Physique - Biologie

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LA DREPANOCYTOSE

Domaine	Science	Sous domaine	Science de la Vie et de la Terre
Section	Scientifique	Option	Math-Physique
Discipline	Biologie	Classe	6ème
Matériel didactique	Craies de couleur	Auteur	SCHOOLAP.COM
Objectif opérationnel	A l'issue de cette leçon, l'enfant sera capable de définir et de décrire la drepanocytose.
Réference	A. Kaleb" Biologie 6èm année " Ed 2015
Activité initiale
Rappel Qu’est-ce qu’un groupe sanguin ?		Rappel Un groupe sanguin est une protéine qui est à la surface du globule rouge.
Motivation Citez quelques les maladies héréditaires que vous connaissez ?		Motivation Les maladies héréditaires sont : l'albinisme, drépanocytose…
Annonce du sujet Qu'allons-nous étudier aujourd’hui ?		Annonce du sujet Aujourd’hui, nous allons étudier la drépanocytose.
Activité principale
Analyse Qu’est-ce que la drépanocytose ?		Analyse LA DREPANOCYTOSE 2.1. Définition : la drépanocytose est une maladie génétique caractérisée par, les globules rouges en forme des faucilles, incapables de jouer leur rôle de transport d’oxygène. On l’appelle également : sicklemie, anémie falciforme ou slow moving. L’hémoglobine anormale s’écrit Hbs et normale est HbA. Elle est causée par une mutation génétique : substitution de l’acide glutamique par la valine en position 6 2.2. Caractéristiques Elle est caractérisée par les hématies en faucille, qui se déchirent par hémolyse. Elles s’agglomèrent en donnant des caillots qui provoquent des douleurs aux membres, abdomen ; Il y a anémie. La prévention est basée sur l’étude génétique. Les deux porteurs donnent :
Synthèse
Qu’est-ce qui provoque la sicklemie ?		La sicklemie est due à la mutation génétique : remplacement de l’acide glutamique en position 6.

Messages Timeline Exceptions Views7 Route Queries14 Models18 Gate Session Request

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